Vitamin B6 status of Ghanaian infants

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Vitamin B6 status, MTHFR and hyperhomocysteinaemia.

Sir, transmethylation pathway is impaired by the possession of a thermolabile MTHFR allele, that the transMild hyperhomocysteinaemia is accepted as a major risk factor for vascular disease, conferring an approxisulphuration pathway will take over. It might therefore be expected that serum vitamin B 6 concentramately three-fold relative risk.1 We have shown previously that homozygosity for the t...

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Vitamin B6 has sometimes been referred to as a ‘vitamin without a deficiency’. Non-specific clinical symptoms and functional losses, such as compromised haem synthesis, immunocompetence and electroencephalographic (EEG) abnormalities, have been observed in experimental (depletion) studies, but ‘spontaneous’ cases of clinical vitamin B6 deficiency in man are rare (for review, see Leklem, 1991; B...

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ژورنال

عنوان ژورنال: The FASEB Journal

سال: 2008

ISSN: 0892-6638,1530-6860

DOI: 10.1096/fasebj.22.1_supplement.873.2